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Prolia


V interakční studii denosumab neovlivňoval farmakokinetiku midazolamu, který je metabolizován
cytochromem P450 3A4 léčivých přípravků metabolizovaných CYP3A4.

Klinické údaje o souběžném podávání denosumabu a substituční hormonální léčby k dispozici, nicméně potenciál pro farmakodynamickou interakci je považován za nízký.

Podle údajů z přechodové studie neovlivnila farmakokinetiku a farmakodynamiku denosumabu u postmenopauzálních žen
s osteoporózou.

Prolia

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About project

A freely available non-commercial project for the purpose of laic drug comparisons at the level of interactions, side effects as well as drug prices and their alternatives

Languages

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