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5-fluorouracil "ebewe"


Farmakoterapeutická skupina: analoga pyrimidinu, ATC kód: L01BC
Fluoruracil je antimetabolit, který jako pyrimidinový antagonista inhibuje dělení buněk tím, že
interferuje se syntézou DNA. Samotný fluoruracil nemá antineoplastickou aktivitu. Tato aktivita
vzniká v těle po enzymatické konverzi fluoruracilu na fosforylované formy 5-fluoruridin a fluordeoxyuridin.

5-fluorouracil "ebewe"

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