Drug combination: Simvastatin-ratiopharm & Prestance &
Drug InteractionSimvastatin-ratiopharm & Prestance
The serum concentration of Simvastatin can be increased when it is combined with Perindopril.
Simvastatin-ratiopharm &
The serum concentration of Simvastatin can be increased when it is combined with Betamethasone.
Prestance &
The serum concentration of Rosuvastatin can be increased when it is combined with Amlodipine.
Food interactions and other recommendationsSimvastatin-ratiopharm: Avoid alcohol. Avoid drastic changes in dietary habit. Avoid taking with grapefruit juice.
Prestance: Avoid natural licorice. Grapefruit down regulates post-translational expression of CYP3A4, the major metabolizing enzyme of amlodipine. Grapefruit, in all forms (e.g. whole fruit, juice and rind), can significantly increase serum levels of amlodipine and may cause toxicity. Avoid grapefruit products while on this medication. Take without regard to meals.
Combination of side effects Combination of common side effects of all medicinesFor some of the comparators, there is not enough information available, contact us by email and we will list the side effects additionally
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