Drug combination: Prestance & Tensiomin
Drug InteractionPrestance & Tensiomin
The risk or severity of adverse effects can be increased when Amlodipine is combined with Captopril.
Food interactions and other recommendationsPrestance: Avoid natural licorice. Grapefruit down regulates post-translational expression of CYP3A4, the major metabolizing enzyme of amlodipine. Grapefruit, in all forms (e.g. whole fruit, juice and rind), can significantly increase serum levels of amlodipine and may cause toxicity. Avoid grapefruit products while on this medication. Take without regard to meals.
Tensiomin: Captopril decreases the excretion of potassium. Salt substitutes containing potassium increase the risk of hyperkalemia. Food decreases absorption by 25 - 40%. Clinical significance is debatable. Herbs that may attenuate the antihypertensive effect of captopril include: bayberry, blue cohash, cayenne, ephedra, ginger, ginseng (American), kola and licorice. High salt intake may attenuate the antihypertensive effect of captopril.
Combination of side effects Combination of common side effects of all medicinesFor some of the comparators, there is not enough information available, contact us by email and we will list the side effects additionally
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Food interactions and other recommendations Prestance: Avoid natural licorice. Grapefruit down regulates post-translational expression of C Y P3 A4, the major metabolizing enzyme of amlodipine. Gra ..more
Prestance & Aspirin
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