Комбинация лекарств: Tensiomin & Prestance
Взаимодействие лекарствTensiomin & Prestance
The risk or severity of adverse effects can be increased when Amlodipine is combined with Captopril.
Продовольственные взаимодействия и другие рекомендацииTensiomin: Captopril decreases the excretion of potassium. Salt substitutes containing potassium increase the risk of hyperkalemia. Food decreases absorption by 25 - 40%. Clinical significance is debatable. Herbs that may attenuate the antihypertensive effect of captopril include: bayberry, blue cohash, cayenne, ephedra, ginger, ginseng (American), kola and licorice. High salt intake may attenuate the antihypertensive effect of captopril.
Prestance: Avoid natural licorice. Grapefruit down regulates post-translational expression of CYP3A4, the major metabolizing enzyme of amlodipine. Grapefruit, in all forms (e.g. whole fruit, juice and rind), can significantly increase serum levels of amlodipine and may cause toxicity. Avoid grapefruit products while on this medication. Take without regard to meals.
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