Drug combination: Paralen 500 & Brufen 400 &
Drug InteractionParalen 500 &
The serum concentration of Simvastatin can be increased when it is combined with Acetaminophen.
Brufen 400 &
The risk or severity of adverse effects can be increased when Ketorolac is combined with Ibuprofen.
Food interactions and other recommendationsParalen 500: Avoid alcohol (may increase risk of hepatotoxicity). Take without regard to meals.
Brufen 400: Avoid alcohol Food delays the time to reach peak plasma concentrations by 30-60 minutes and reduces peak plasma concentrations by 30-50%. Extent of absorption is unaffected. Take with food to reduce gastric irritation.
Combination of side effects Combination of common side effects of all medicinesFor some of the comparators, there is not enough information available, contact us by email and we will list the side effects additionally
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