Drug combination: Apo-amlo 5 & Depresinal

Compared drugs
Apo-amlo 5 (amlodipine)
Depresinal (escitalopram)

Drug Interaction

No interactions found

Food interactions and other recommendations

Apo-amlo 5: Avoid natural licorice. Grapefruit down regulates post-translational expression of CYP3A4, the major metabolizing enzyme of amlodipine. Grapefruit, in all forms (e.g. whole fruit, juice and rind), can significantly increase serum levels of amlodipine and may cause toxicity. Avoid grapefruit products while on this medication. Take without regard to meals.
Depresinal: Take without regard to meals.

Combination of side effects

Combination of common side effects of all medicines

Abdominal Pain
Apo-amlo 5 (common)
Depresinal (common)

Dizziness
Apo-amlo 5 (common)
Depresinal (very common)

Edema
Apo-amlo 5 (common)
Depresinal (uncommon)

Fatigue
Apo-amlo 5 (common)
Depresinal (common)

Flushing
Apo-amlo 5 (uncommon)
Depresinal (uncommon)

Headache
Apo-amlo 5 (common)
Depresinal (very common)

Nausea
Apo-amlo 5 (common)
Depresinal (very common)

Palpitation
Apo-amlo 5 (uncommon)
Depresinal (common)

Somnolence
Apo-amlo 5 (uncommon)
Depresinal (very common)

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Apo-amlo & Depresinal

Food interactions and other recommendations Apo-amlo 5: Avoid natural licorice. Grapefruit down regulates post-translational expression of C Y P3 A4, the major metabolizing enzyme of amlodipine. Gr ..more