Drug combination: Wobenzym & Trombex & Lanzul & Prestance & Tulip

Compared drugs
Wobenzym (trypsin, combinations)
Trombex (clopidogrel)
Lanzul (lansoprazole)
Prestance (perindopril and amlodipine)
Tulip (atorvastatin)
Drug Interaction
Trombex & Lanzul
The serum concentration of the active metabolites of Clopidogrel can be reduced when Clopidogrel is used in combination with Lansoprazole resulting in a loss in efficacy.

Trombex & Prestance
The therapeutic efficacy of Clopidogrel can be decreased when used in combination with Amlodipine.

Lanzul & Tulip
The risk or severity of adverse effects can be increased when Lansoprazole is combined with Atorvastatin.

Prestance & Tulip
The risk or severity of adverse effects can be increased when Amlodipine is combined with Atorvastatin.

Food interactions and other recommendations

Lanzul: Avoid alcohol. Food reduces bioavailabilty, but this has very little clinical impact. Take 30-60 minutes before meals.
Prestance: Avoid natural licorice. Grapefruit down regulates post-translational expression of CYP3A4, the major metabolizing enzyme of amlodipine. Grapefruit, in all forms (e.g. whole fruit, juice and rind), can significantly increase serum levels of amlodipine and may cause toxicity. Avoid grapefruit products while on this medication. Take without regard to meals.
Tulip: Avoid alcohol. Avoid drastic changes in dietary habit. Avoid taking grapefruit or grapefruit juice throughout treatment. Grapefruit can significantly increase serum levels of this product. Food may decrease maximum plasma levels and area under the curve, but this is clinically inconsequential according to the manufacturer. Take with low fat meal.
 
Combination of side effects
Combination of common side effects of all medicines
For some of the comparators, there is not enough information available, contact us by email and we will list the side effects additionally
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Wobenzym & Trombex & Lanzul & Prest..

  Trombex & Lanzul  The serum concentration of the active metabolites of Clopidogrel can be reduced when Clopidogrel is used in combination with Lansoprazole resulting in a loss in efficacy. ..more

Trombex & Elicea & Prestarium & Age..

  Trombex & Agen 5  The therapeutic efficacy of Clopidogrel can be decreased when used in combination with Amlodipine.   Trombex &   The serum concentration of Amodiaquine can be incr ..more

Prestance & Aspirin & Lokren &

  Prestance & Lokren  The risk or severity of adverse effects can be increased when Betaxolol is combined with Amlodipine.   Prestance &   The serum concentration of Rosuvastatin can ..more

Trombex & Detralex

Food interactions and other recommendations Combination of common side effects of all medicines  ..more

Trombex & Novalgin

Food interactions and other recommendations Combination of common side effects of all medicines  ..more

Wobenzym & Trombex & Glucophage & B..

  Trombex &   The serum concentration of Amodiaquine can be increased when it is combined with Clopidogrel.   Glucophage xr &   The risk or severity of adverse effects can be increase ..more

Wobenzym & Prestance & Salazopyrin ..

  Prestance &   The serum concentration of Rosuvastatin can be increased when it is combined with Amlodipine.   Salazopyrin en &   The risk or severity of adverse effects can be incre ..more

Prestance & Aspirin & Lokren

  Prestance & Lokren  The risk or severity of adverse effects can be increased when Betaxolol is combined with Amlodipine.   Aspirin & Lokren  Acetylsalicylic acid may decrease the an ..more

Trombex & Salazopyrin &

  Trombex &   The serum concentration of Amodiaquine can be increased when it is combined with Clopidogrel.   Salazopyrin en &   The risk or severity of adverse effects can be increas ..more

Lanzul & Salazopyrin & Pms-testoster..

  Lanzul & Tulip  The risk or severity of adverse effects can be increased when Lansoprazole is combined with Atorvastatin.   Salazopyrin en & Aspirin protect 100  The risk or severit ..more

Trombex & Egilok & Ebrantil & Nolpa..

  Trombex & Nolpaza  The serum concentration of the active metabolites of Clopidogrel can be reduced when Clopidogrel is used in combination with Pantoprazole resulting in a loss in efficacy. ..more

Prestance & Aspirin

Food interactions and other recommendations Prestance: Avoid natural licorice. Grapefruit down regulates post-translational expression of C Y P3 A4, the major metabolizing enzyme of amlodipine. Gra ..more

Trombex & Novalgin

Food interactions and other recommendations Combination of common side effects of all medicines  ..more

Trombex & Dalacin &

  Trombex &   The serum concentration of Amodiaquine can be increased when it is combined with Clopidogrel.   Dalacin &   The therapeutic efficacy of Clindamycin can be decreased when ..more

Prestance & Xyzal & Cavinton & Neur..

  Prestance & Cavinton forte  Amlodipine may increase the hypotensive activities of Vinpocetine.   Xyzal & Neurol 0,25  The risk or severity of adverse effects can be increased when A ..more

Trombex & Dalacin

Food interactions and other recommendations Dalacin: Take with food.  Combination of common side effects of all medicines  Constipation rash  Headache  Nausea  Itching  Vomiting ..more

Trombex & Helicid &

  Trombex & Helicid 20 zentiva  Omeprazole may decrease the antiplatelet activities of Clopidogrel.   Trombex &   The serum concentration of Amodiaquine can be increased when it is co ..more

Trombex & Tritace & Egilok & Nolpaz..

  Trombex & Nolpaza  The serum concentration of the active metabolites of Clopidogrel can be reduced when Clopidogrel is used in combination with Pantoprazole resulting in a loss in efficacy. ..more

Wobenzym & Trombex &

  Trombex &   The serum concentration of Amodiaquine can be increased when it is combined with Clopidogrel.  Food interactions and other recommendations Combination of common side effects o ..more

Trombex & Novalgin

Food interactions and other recommendations Combination of common side effects of all medicines  ..more

Trombex & Wobenzym

Food interactions and other recommendations Combination of common side effects of all medicines  ..more

Trombex & Helicid

  Trombex & Helicid 20 zentiva  Omeprazole may decrease the antiplatelet activities of Clopidogrel.  Food interactions and other recommendations Helicid 20 zentiva: Avoid alcohol. Ta ..more

Wobenzym & Trombex & Lanzul & Prest..

  Trombex & Lanzul  The serum concentration of the active metabolites of Clopidogrel can be reduced when Clopidogrel is used in combination with Lansoprazole resulting in a loss in efficacy. ..more

Trombex & Ibalgin

Food interactions and other recommendations Ibalgin 400: Avoid alcohol Food delays the time to reach peak plasma concentrations by 30-60 minutes and reduces peak plasma concentrations by 30-50%. ..more

Trombex & Stacyl

  Trombex & Stacyl  The risk or severity of adverse effects can be increased when Clopidogrel is combined with Acetylsalicylic acid.  Food interactions and other recommendations Stacyl: ..more

Trombex & Stacyl

  Trombex & Stacyl  The risk or severity of adverse effects can be increased when Clopidogrel is combined with Acetylsalicylic acid.  Food interactions and other recommendations Stacyl: ..more

Trombex & Stacyl

  Trombex & Stacyl  The risk or severity of adverse effects can be increased when Clopidogrel is combined with Acetylsalicylic acid.  Food interactions and other recommendations Stacyl: ..more

About project

A freely available non-commercial project for the purpose of laic drug comparisons at the level of interactions, side effects as well as drug prices and their alternatives

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